Wang Y, Mei J, Tang Y, et al. Development and validation of a clinical prediction model for first fall in early Parkinson's disease: a study of two fall-naive cohorts. Frontiers in Aging Neuroscience. 2026;18:1735524. DOI 10.3389/fnagi.2026.1735524
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DOI: 10.3389/fnagi.2026.1735524
Bibliographic record from the original reports
Access labels embedded in these original reference strings are historical. Current access and exact checked components are stated separately below.
Wang Y, Mei J, Tang Y, et al. Development and validation of a clinical prediction model for first fall in early Parkinson's disease: a study of two fall-naive cohorts. Frontiers in Aging Neuroscience. 2026;18:1735524. DOI 10.3389/fnagi.2026.1735524
Conditions: COND-PD Parkinson’s disease
Scoped audit evidence
These are source- and component-level audit summaries as of 3 October 2026. Access and comparison scope can differ by report; none certifies every result or the underlying raw data.
Parkinson’s disease — gait
- access status: primary_body_retrieved
Latest listed audit check, current for its stated components. Later recovery/refinement here supersedes earlier access limitations only where explicitly stated; it does not resolve unrelated source contradictions.
GaitP83 event split confirmed from originalFigure1:49/283training,19/120internal,31/150external. Figure6 actualaxes label observed/predictedriskof firstfall but estimates concentratearound.75-1despiteobserved3yearincidence.169/.207;report appropriately requestsprobabilityorientationclarification. Source locator: Visual originalPMC12953559 Figure1 audit evidence record audit evidence record;fullbodyMethods/Table3 previouslychecked Limit: Cannot conclude underlying calibration computationwrong fromfigurealone. Actual model probability scale needsauthorcodeclarification. Add internalvalidationusedforselectioncaveat.
Earlier audit check 1 (historical evidence record). Its access limitations are superseded wherever the latest check above explicitly closes them. Retained for the distinct components and provenance, not as a current access statement.
Gait P42-43,P83-85:283/120/150 cohort sizes;68 PPMI and31 local first falls;36-month horizon;5 predictors BMI/asymptomatic OH/MoCA/GDS/PIGD;external C-index .825(.768-.882),36m AUC .884(.829-.939);imputation before split;complete outcome follow-up selection;clinical composite not gait-only;geographic external cohort Source locator: s5 Study design;s7 Clinical assessment;s9 Survival outcome;s11 Statistical analysis;s14 Table1;s16 outcomes;s18 Table2;s20 Table3 Limit: 49/19 split event counts and calibration-axis ambiguity require Figure1/6 image inspection, not established from captions. External validation preserved but internal validation was also used to select five versus six predictors, an additional potential optimism concern. Table1 has apparently swapped PPMI/local entries for anxious mood and daytime sleepiness; source issue, not a reported-data error in this review.
Limitations: Only scoped comparisons, not whole-paper certification.
Linked audit findings
Reports citing this source
- Gait analysis and prognosis in Parkinson’s disease · reference 4 · original reference
Update record
- 2026-10-03: Created from the supplied reports and final scoped audit. New evidence should be appended with source version, access date, exact locator and affected report links.
Updating the wiki · Evidence and status guide