Increased fracture risk in Parkinson’s disease - An exploration of mechanisms and consequences for fracture prediction with FRAX.
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DOI: 10.1016/j.bone.2022.116651
Bibliographic record from the original reports
Access labels embedded in these original reference strings are historical. Current access and exact checked components are stated separately below.
Schini M, Bhatia P, Shreef H, et al. Increased fracture risk in Parkinson’s disease: an exploration of mechanisms and consequences for fracture prediction with FRAX. Bone. 2023;168:116651. Original article
Schini M, Bhatia P, Shreef H, Johansson H, Harvey NC, Lorentzon M, et al. Increased fracture risk in Parkinson’s disease: An exploration of mechanisms and consequences for fracture prediction with FRAX. Bone. 2023;168:116651. DOI 10.1016/j.bone.2022.116651
Conditions: COND-PD Parkinson’s disease
Scoped audit evidence
These are source- and component-level audit summaries as of 3 October 2026. Access and comparison scope can differ by report; none certifies every result or the underlying raw data.
Parkinson’s disease — strength
- access status: full_main_text_available
STR-69-03
STR-69-01
STR-69-02
Limitations: Only current scoped checks; archived captures not authenticated against live originals.
Parkinson’s disease — transfer
- access status: archived_primary_html_capture
5,212 women aged ≥75, 47 with PD; 11 PD women sustained 12 fractures. Nurse-observed single armless rise uses three ability categories. PD hazard ratio adjusted for STS 2.16 (1.19–3.93), n=5,158; strength-adjusted HR 1.70 (.81–3.59), n=4,611 versus base n=5,161. Original supplement concerns sway.
Limitations: Only the enumerated transfer-relevant components were adjudicated. Source availability does not imply every statement, supplement, figure or raw datum was checked.
Parkinson’s disease strength
- current access: full_main_text_available
- primary version: Archived licensed publisher HTML/text capture; separately recovered original supplement inspected
Parkinson’s disease strength component — Fracture sample definition, force assay, hazard-ratio exposure and exact model denominators
The cohort comprises women aged≥75 years; Results gives 43 definite PD cases plus four probable cases receiving dopaminergic treatment. An in-house load cell measured maximum isometric quadriceps force bilaterally. Table 2 treats PD status as the exposure: height/treatment-adjusted HR 2.25 [1.24, 4.08], n 5161, versus HR 1.70 [.81, 3.59], n 4611 after adding quadriceps strength. Different model samples prevent attributing all attenuation to strength. The report’s values and interpretation match.
Source locator: https://doi.org/10.1016/j.bone.2022.116651; Library original archived audit evidence Methods2.1–2.4, Results3.1, Table2 and footnote
Limitations: AI-assisted comparison with archived licensed capture; transcription accuracy was not independently verified against the live publisher original.
Parkinson’s disease strength component — Recovered supplement content and historical-access boundary
The separately recovered original Schini supplement contains only a sway-path comparison table. It adds no per-strength fracture hazard ratio or chair-rise prognostic model. All strength-related numeric claims in P 502 are in main Table 2, already checked. A licensed archived source now supports current access; this does not reproduce the report author’s original reading process.
Source locator: https://doi.org/10.1016/j.bone.2022.116651; archived audit evidence
Limitations: AI-assisted source comparison; no raw-data verification.
Reports citing this source
- Sit to stand and functional transfer assessment and prognosis in Parkinson’s disease · reference 58 · original reference
- Strength muscle power and rapid force production assessment in Parkinson’s disease · reference 69 · original reference
Update record
- 2026-10-03: Created from the supplied reports and final scoped audit. New evidence should be appended with source version, access date, exact locator and affected report links.
Updating the wiki · Evidence and status guide