TR-03 · unverified temporal prespecification
Classification and audit outcome: unverified temporal prespecification; supported provenance qualification.
Finding
“Prespecified” modifies the full-group RFD interaction. The published Methods describe that analysis, but the current registry lists only the UPDRS outcome and no dated RFD analysis plan was recovered. Numerical p=.064 and subgroup p=.049 are supported.
Current amendment or qualification
Delete “prespecified” or provide a dated protocol/statistical analysis plan substantiating advance specification. Do not label the analysis post hoc without evidence.
Integration note: No dated analysis plan was established in this QA. Remove unsupported prespecified adjective or obtain dated plan; current registry absence does not prove post hoc analysis.
Remaining limitation: No dated analysis plan was established in this QA. Remove unsupported prespecified adjective or obtain dated plan; current registry absence does not prove post hoc analysis.
Evidence and provenance
Malling Methods/Statistics; ClinicalTrials.gov NCT02125032 current outcomesModule.
Affected reports
Original audit locator(s): P0178
Audit corrections describe the report only where that classification is explicit. A disagreement within a study, missing protocol, statistical query, access upgrade or optional addition is not silently converted into a report error or a new clinical threshold.
Audit register · Unresolved evidence queue
Linked knowledge pages
- COND-PD Parkinson’s disease
- TEST-RFD Rate of force and torque development
Located in this vault
Mapping status: exact. An exact location match is not an additional empirical verification.